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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Acromegaly


Other Names for this Disease

  • Growth hormone excess
  • Pituitary giant
  • Somatotroph adenoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Acromegaly is a hormonal disorder that results from the pituitary gland producing too much growth hormone (GH). It is most often diagnosed in middle-aged adults, although symptoms can appear at any age. Signs and symptoms include abnormal growth and swelling of the hands and feet; bone changes that alter various facial features; arthritiscarpal tunnel syndrome; enlargement of body organs; and various other symptoms. The condition is usually caused by benign tumors on the pituitary called adenomas. Rarely, it is caused by tumors of the pancreas, lungs, and other parts of the brain. Acromegaly is usually treatable but when left untreated, it can result in serious illness and premature death. When GH-producing tumors occur in childhood, the disease that results is called gigantism rather than acromegaly.[1]
Last updated: 4/29/2011

References

  1. Acromegaly. NEMDIS. http://www.endocrine.niddk.nih.gov/pubs/acro/acro.htm. Accessed 4/29/2011.
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Please contact us with your questions about Acromegaly. We will answer your question and update these pages with new resources and information.

Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acromegaly. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Growth hormone excess
  • Pituitary giant
  • Somatotroph adenoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.