Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Allan-Herndon-Dudley syndrome


Other Names for this Disease

  • AHDS
  • Allan-Herndon syndrome
  • Mental retardation and muscular atrophy
  • Monocarboxylate transporter-8 deficiency
  • T3 resisitence
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Symptoms

Newline Maker

What are the symptoms of Allan-Herndon-Dudley syndrome?

Allan-Herndon-Dudley syndrome causes moderate to severe intellectual disability and problems with movement. They also have impaired speech and a limited ability to communicate. Most children with this condition have weak muscle tone (hypotonia) and underdevelopment of many muscles (muscle hypoplasia). As they get older, they often develop joint deformities called contractures, which restrict the movement of certain joints. Abnormal muscle stiffness (spasticity), muscle weakness, and involuntary movements of the arms and legs also limit mobility. As a result, many people with Allan-Herndon-Dudley syndrome are unable to walk independently and become wheelchair-bound by adulthood.[1] 
Last updated: 6/12/2014

References
  1. Allan-Herndon-Dudley syndrome. Genetics Home Reference (GHR). April 2013; http://ghr.nlm.nih.gov/condition/allan-herndon-dudley-syndrome. Accessed 6/12/2014.


Other Names for this Disease
  • AHDS
  • Allan-Herndon syndrome
  • Mental retardation and muscular atrophy
  • Monocarboxylate transporter-8 deficiency
  • T3 resisitence
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.