Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Spinocerebellar ataxia 8

Other Names for this Disease
  • SCA8
  • Spinocerebellar ataxia type 8
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Spinocerebellar ataxia type 8 (SCA8) is an inherited neurodegenerative condition characterized by slowly progressive ataxia (problems with movement, balance, and coordination). This condition typically occurs in adulthood and usually progresses over decades. Common initial symptoms include dysarthria, slow speech, and trouble walking. Some affected individuals experience nystagmus and other abnormal eye movements. Life span is typically not shortened. This condition is inherited in an autosomal dominant manner, although not all individuals with abnormalities in the disease-causing gene will develop the disease (called reduced penetrance).[1][2]
Last updated: 1/2/2012


  1. Ikeda Y, Dalton JC, Day JW & Ranum LPW. Spinocerebellar Ataxia Type 8. GeneReviews. February 2007; Accessed 10/12/2011.
  2. Yoshio Ikeda, Joline C Dalton, John W Day, Laura PW Ranum. Spinocerebellar Ataxia Type 8. GeneReviews. February 7, 2007; Accessed 1/2/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Spinocerebellar ataxia 8 have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Spinocerebellar ataxia 8. Click on the link to view a sample search on this topic.

Insurance Issues