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Genetic and Rare Diseases Information Center (GARD)

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Multiple endocrine neoplasia type 2A

Other Names for this Disease
  • MEN 2A
  • MEN-2A syndrome
  • Pheochromocytoma and amyloid producing medullary thyroid carcinoma
  • PTC syndrome
  • Sipple syndrome
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Your Question

How rare is multiple endocrine neoplasia type 2A? How is this condition inherited?

Our Answer

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How rare is multiple endocrine neoplasia type 2A?

Multiple endocrine neoplasia type 2 affects an estimated 1 in 30,000 to 35,000 people. Among the subtypes of multiple endocrine neoplasia type 2, type 2A is the most common form, making up 70-80% of cases.[1][2]
Last updated: 2/11/2011

How is multiple endocrine neoplasia type 2A inherited?

Multiple endocrine neoplasia type 2A (MEN 2A) is inherited in an autosomal dominant pattern. A person with MEN 2A often inherits the altered RET gene from one parent with the condition.[1]  
Last updated: 2/11/2011