Other Names for this Disease
- Cellular schwannoma (histologic variant)
- Melanotic schwannoma (histologic variant)
- Plexiform schwannoma (histologic variant)
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Schwannomas are not considered hereditary if an individual develops only one schwannoma, unless there is also a family history of schwannoma. However, individuals who develop more than one schwannoma are thought to have a genetic predisposition to develop these tumors. Multiple schwannomas can be caused by one of two hereditary conditions, neurofibromatosis type 2 or schwannomatosis. Two articles studied individuals with schwannoma: one found that only 5% of affected individuals developed multiple schwannomas; the other showed that 10% developed multiple schwannomas. This suggests that 90-95% of individuals with schwannoma do not have a genetic condition and developed the schwannoma by chance.
Last updated: 7/22/2014
- Antinheimo J, Sankila R, Carpen O, Pukkala E, Sainio M, Jaaskelainen J.. Population-based analysis of sporadic and type 2 neurofibromatosis-associated meningiomas and schwannomas. Neurology. 2000; 54(1):71-76. http://www.ncbi.nlm.nih.gov/pubmed/10636128. Accessed 7/22/2014.
- Gonzalvo A, Fowler A, Cook RJ, Little NS, Wheeler H, McDonald KL, Biggs MT. Schwannomatosis, sporadic schwannomatosis, and familial schwannomatosis: a surgical series with long-term follow-up. Clinical article.. Journal of Neurosurgery. 2011; 113(3):752-765. http://www.ncbi.nlm.nih.gov/pubmed/20932094. Accessed 7/22/2014.