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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Microcoria, congenital


Other Names for this Disease

  • Congenital microcoria
  • Congenital miosis
  • MCOR
  • Miosis, congenital
  • Pinhole pupils
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Overview

What is congenital microcoria?

What are the symptoms of congenital microcoria?

Is congenital microcoria genetic?

What is congenital microcoria?

Congenital microcoria is a rare anomaly of the pupils. It is characterized by pupils of less than 2 mm diameter and is caused by the underdevelopment of the dilator pupillae muscle of the iris. This anomaly is associated with nearsightedness and glaucoma.[1][2]
Last updated: 7/19/2013

What are the symptoms of congenital microcoria?

Symptoms of congenital microcoria include small pupil size (< 2 mm), iris transillumination defects, and reduced or absent response to mydriatic drugs.[1]
Last updated: 7/19/2013

Is congenital microcoria genetic?

Both inherited and sporadic cases of congenital microcoria have been reported in the medical literature. Studies of families with this anomaly suggests an autosomal dominant mode of inheritance.[1]
Last updated: 7/19/2013

References
  1. Rouillac C, Roche O, Marchant D, Bachner L, Kobetz A, Toulemont PJ, Orssaud C, Urvoy M, Odent S, Le Marec B, Abitbol M, Dufier JL. Mapping of a Congenital Microcoria Locus to 13q31-q32. Am. J. Hum. Genet. 1998;
  2. Ramprasad VL, Sripriya S, Ronnie G, Nancarrow D, Saxena S, Hemamalini A, Kumar D, Vijaya L, Kumaramanickavel G. Molecular Vision. 2005; http://www.molvis.org/molvis/v11/a112/. Accessed 3/17/2008.


Other Names for this Disease
  • Congenital microcoria
  • Congenital miosis
  • MCOR
  • Miosis, congenital
  • Pinhole pupils
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.