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Genetic and Rare Diseases Information Center (GARD)

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Lewy body dementia


Other Names for this Disease

  • Autosomal dominant diffuse Lewy body disease
  • Diffuse Lewy body disease
  • DLB
  • Lewy body disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Lewy bodies dementia is one of the most common types of dementia. The central feature of this condition is progressive cognitive decline, combined with three additional defining features: (1) fluctuations in alertness and attention, such as frequent drowsiness, lethargy, lengthy periods of time spent staring into space, or disorganized speech; (2) recurrent visual hallucinations, and (3) parkinsonian motor symptoms, such as rigidity and the loss of spontaneous movement. Although the exact cause of this condition is unknown, symptoms result from the build-up of abnormal structures, called Lewy bodies, inside the brain. This condition usually occurs sporadically, in people with no known family history of the disease. However, rare familial cases have been reported.[1]
Last updated: 1/12/2012

References

  1. NINDS Dementia With Lewy Bodies Information Page. National Institute of Neurological Disorders and Stroke (NINDS). December 2011; http://www.ninds.nih.gov/disorders/dementiawithlewybodies/dementiawithlewybodies.htm. Accessed 1/12/2012.
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Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Lewy body dementia. Click on the link to view a sample search on this topic.

Insurance Issues

Other Names for this Disease
  • Autosomal dominant diffuse Lewy body disease
  • Diffuse Lewy body disease
  • DLB
  • Lewy body disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.