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Genetic and Rare Diseases Information Center (GARD)

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Lactate dehydrogenase A deficiency

Other Names for this Disease
  • Glycogen Storage Disease XI
  • Lactate dehydrogenase deficiency type A
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Your Question

How common is lactate dehydrogenase A deficiency and how might this condition be managed (for instance, should complex carbohydrates be avoided)?  

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How common is lactate dehydrogenase deficiency?

Lactate dehydrogenase deficiency is a rare disorder. In Japan, this condition affects 1 in 1 million individuals; the prevalence of lactate dehydrogenase deficiency in other countries is unknown.[1]
Last updated: 3/27/2012

How might lactate dehydrogenase deficiency type A be treated?

For many people with metabolic muscle diseases, the only treatment needed is to understand what activities and situations tend to trigger attacks of rhabdomyolysis. In addition, some people with metabolic disorders have benefited from dietary changes. For instance, there is evidence that those with carbohydrate-processing problems may be helped by a high-protein diet, while those with difficulty processing fats may do well on a diet high in carbohydrates and low in fat.[2]

We encourage you to consult with your healthcare provider for more information about management of lactate dehydrogenase A deficiency. A professional staff member through a Muscular Dystrophy Association (MDA) clinic can also help you design a specific plan suited for your metabolic disorder and individual needs.

Last updated: 3/27/2012