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Genetic and Rare Diseases Information Center (GARD)

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Hypomelanosis of Ito


Other Names for this Disease

  • Incontinentia pigmenti achromians
  • Incontinentia pigmenti type 1 (formerly)
  • IPA
  • ITO
  • Ito hypomelanosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Hypomelanosis of Ito, also called incontinentia pigmenti achromians, is a rare birth defect that causes streaked, whirled, or mottled patches of light-colored skin. These skin changes often develop within the first two years of life. Other symptoms may include varying degrees of learning disability, seizures, increased body hair, scoliosis, and strabismus. The underlying cause of the condition is currently unknown. Girls tend to be affected more commonly than boys.[1][2]
Last updated: 2/24/2012

References

  1. Incontinentia pigmenti achromians. MedlinePlus. 2011; http://www.nlm.nih.gov/medlineplus/ency/article/001461.htm. Accessed 2/24/2012.
  2. Vergine G. Ito hypomelanosis. Orphanet. 2008; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=435. Accessed 2/24/2012.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

2 question(s) from the public on Hypomelanosis of Ito have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hypomelanosis of Ito. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles

Other Names for this Disease
  • Incontinentia pigmenti achromians
  • Incontinentia pigmenti type 1 (formerly)
  • IPA
  • ITO
  • Ito hypomelanosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.