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Genetic and Rare Diseases Information Center (GARD)

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IBIDS syndrome

Other Names for this Disease
  • Ichtyosis, Brittle hair, Intellectual impairment, Decreased fertility, and Short stature
  • Tay syndrome
  • Trichothiodystrophy with congenital ichtyosis
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What causes Tay syndrome? How is it inherited?

Although Tay syndrome is known to be genetic, the gene(s) associated with the condition is(are) unknown. Tay syndrome is inherited in an autosomal recessive pattern [1], which means two copies of the gene in each cell are altered (mutated). If both parents carry the gene for Tay syndrome, their children have a 25% chance of being affected with Tay syndrome. Additionally, each child has a 50% chance of being an unaffected carrier, like their parents, and a 25% chance of being a non-carrier.[1]
Last updated: 7/30/2013

  1. Jamhekar SD, Dhongade AR. Tay syndrome. Indian J Pediatr. 2008 Mar; 75(3):288-290.