Your QuestionMy 12-year-old daughter has hypothalamic dysfunction. She has been having the following symptoms: bed wetting, anger, hitting others, irregular breathing, excessive thirst, obesity, difficulty regulating body temperature, and requires a bipap machine while sleeping. Could you tell us more about this condition and its treatments?
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- Birth defects of the brain or hypothalamus (e.g. holoprosencephaly, septo-optic dysplasia)
- Genetic disorders (e.g. Prader-Willi syndrome, growth hormone deficiency)
- Eating disorders (e.g. anorexia, bulimia)
- Tumors (e.g. craniopharyngiomas, germinomas, meningiomas, gliomas, ependymomas, and gliomas of the optic nerve)
- Head trauma (e.g. boxing and varied injuries, birth trauma)
- Bacterial, viral, or fungal infections
- Autoimmune disorders (e.g. sarcoidosis)
- Cranial radiation
- Too much iron
In some cases of hypothalamic dysfunction, the cause is unknown; these cases are referred to as having idiopathic hypothalamic dysfunction.
- Hypothalamic dysfunction. MedlinePlus Medical Encyclopedia. November 23, 2009; http://www.nlm.nih.gov/medlineplus/ency/article/001202.htm. Accessed 4/13/2010.
- Kronenberg: Williams Textbook of Endocrinology, 11th ed. Philadelphia: Saunders, An Imprint of Elsevier; 2008;
- Huppke P, Heise A, Rostasy K, Huppke B, Gartner J. Immunoglobulin therapy in idiopathic hypothalamic dysfunction. Pediatr. Neurol.. 2009 Sep;