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Genetic and Rare Diseases Information Center (GARD)

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Hallermann-Streiff syndrome

Other Names for this Disease
  • Francois dyscephalic syndrome
  • Hallermann Streiff Francois syndrome
  • Hallermann Streiff syndrome
  • HSS
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How is Hallermann-Streiff syndrome inherited?

The majority of cases of Hallermann-Streiff syndrome appear to be sporadic (occurring in individuals with no history of the condition in the family).[1][2] There have been reports of affected individuals having multiple, unaffected children. Although some have reported it appears to be inherited in an autosomal recessive manner in a small number of cases, others have argued that there is little evidence for this being a recessively inherited disorder.[3][4] Therefore, the mode of inheritance of the condition remains unclear.
Last updated: 7/23/2012

  1. Graham JM. Hallermann Streiff Syndrome. National Organization for Rare Disorders (NORD). 2008; Accessed 3/19/2010.
  2. Hallermann-Streiff-Francois syndrome. Orphanet. 2006; Accessed 3/19/2010.
  3. Hallerman-Streiff Syndrome. Online Mendelian Inheritance in Man (OMIM). 2010; Accessed 3/19/2010.
  4. Hallermann Streiff Syndrome. NORD. April 11, 2012; Accessed 7/23/2012.