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Genetic and Rare Diseases Information Center (GARD)

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Limb-girdle muscular dystrophy, type 2C


Other Names for this Disease

  • Adhalin deficiency, secondary
  • DMDA
  • DMDA1
  • Duchenne-like muscular dystrophy, autosomal recessive, type 1
  • Gamma-sarcoglycanopathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Question

I live in Serbia, and I'm looking all around the world to find somebody who may give me hope and help me with my problem. In 1998 when I was 12-years-old, I suddenly felt some pains in my leg muscles and from that moment I have problems with my all body muscles. Now I am 23 and I still walk on my own but it is very hard. Two years ago I was diagnosed with gamma-sarcoglycanopathy (LGMD2C). 

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is limb-girdle muscular dystrophy type 2C?

Limb-girdle muscular dystrophy type 2C (LGMD2C) is a condition that affects the muscles and is caused by mutations in the gamma-sarcoglycan gene.[1] This condition belongs to a group of muscle disorders called limb-girdle muscular dystrophies, which are characterized by progressive loss of muscle bulk and symmetrical weakening of voluntary muscles, primarily those in the shoulders and around the hips.[2] LGMD2C is inherited in an autosomal recessive manner, and treatment is based on an individual's symptoms.[2]
Last updated: 4/14/2009

What treatment is available for limb-girdle muscular dystrophy?

There is no specific treatment for limb-girdle muscular dystrophy.[3] Management of the condition is based on the person's symptoms and subtype (if known). The GeneReview article on limb-girdle muscular dystrophy lists the following approach for medical management of the condition:

  • Weight control to avoid obesity
  • Physical therapy and stretching exercises to promote mobility and prevent contractures
  • Use of mechanical aids such as canes, walkers, orthotics, and wheelchairs as needed to help ambulation and mobility
  • Monitoring and surgical intervention as needed for orthopedic complications such as foot deformity and scoliosis
  • Monitoring of respiratory function and use of respiratory aids when indicated
  • Monitoring for evidence of cardiomyopathy in those subtypes with known occurrence of cardiac involvement
  • Social and emotional support and stimulation to maximize a sense of social involvement and productivity and to reduce the sense of social isolation common in these disorders
Last updated: 4/14/2009

References
Other Names for this Disease
  • Adhalin deficiency, secondary
  • DMDA
  • DMDA1
  • Duchenne-like muscular dystrophy, autosomal recessive, type 1
  • Gamma-sarcoglycanopathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.