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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Acute posterior multifocal placoid pigment epitheliopathy


Other Names for this Disease

  • Acute multifocal placoid pigment epitheliopathy
  • Acute placoid pigment epitheliopathy
  • AMPPE
  • APMPPE
  • Epitheliopathy, acute posterior multifocal placoid pigment
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Treatment

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How might acute posterior multifocal placoid pigment epitheliopathy (APMPPE) be treated?

The treatment of APMPPE is somewhat controversial, but the general consensus is that no treatment seems to alter the course of the ocular lesions. In cases complicated by subretinal neovascularization (growth of new blood vessels), laser photocoagulation may be useful.[1]

In most cases, the lesions resolve spontaneously and no therapy is required. Some clinicians have used corticosteroids (which suppress inflammation) to treat the ocular findings and any severe systemic involvement. However, there is no evidence that treatment with corticosteroids affects the visual outcome.[1] The use of steroids has also been suggested when treating cases where the macula is involved.[2] Cycloplegics may be useful for severe iritis, which is an uncommon finding.[1]

It is recommended that people with questions about treatment options for themselves or family members speak with their health care provider.
Last updated: 9/9/2014

References
  1. Lakshmana M Kooragayala. Acute Multifocal Placoid Pigment Epitheliopathy. Medscape Reference. September 16, 2013; http://emedicine.medscape.com/article/1225531-overview. Accessed 9/9/2014.
  2. Grkovic D, Oros A, Bedov T, Karadžic J, Gvozdenovic L, Jovanovic S. Acute posterior multifocal placoid pigment epitheliopathy-retinal "white dot syndrome". Med Glas (Zenica). February, 2013; 10(1):194-196. Accessed 9/9/2014.


Other Names for this Disease
  • Acute multifocal placoid pigment epitheliopathy
  • Acute placoid pigment epitheliopathy
  • AMPPE
  • APMPPE
  • Epitheliopathy, acute posterior multifocal placoid pigment
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.