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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Epitheliopathy, acute posterior multifocal placoid pigment


Other Names for this Disease

  • Acute multifocal placoid pigment epitheliopathy
  • Acute placoid pigment epitheliopathy
  • Acute posterior multifocal placoid pigment epitheliopathy
  • AMPPE
  • APMPPE
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Question

My husband has been diagnosed with acute posterior multifocal placoid pigment epitheliopathy. Is the vision loss associated with this condition permanent?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is acute posterior multifocal placoid pigment epitheliopathy?

Acute posterior multifocal placoid pigment epitheliopathy is an eye disorder characterized by the impairment of central vision in one or both eyes. It mainly affects young adults. In most cases, the disorder resolves within a few weeks without loss of visual acuity. While the cause is unknown, approximately one-third of cases appear to follow an influenza-like illness.[1]
Last updated: 12/30/2009

Is the vision loss associated with acute posterior multifocal placoid pigment epitheliopathy permanent?

In most cases, the disorder resolves within a few weeks without loss of visual acuity.[1] In many patients, visual acuity returns to the range of 20/20 to 20/40. Initial visual recovery is often rapid, but final recovery may take up to 6 months.[2] In a small number of cases, vision does not improve.[1][2][3] Many of these patients have permanent visual loss due to subretinal neovascularization. Others may have long-term functional ocular symptoms such as scotomata.[2]
Last updated: 12/30/2009

What is the prognosis for individuals with acute posterior multifocal placoid pigment epitheliopathy?

Patients may be reassured that in spite of significant visual loss, the visual decrease is usually transient and many patients regain relatively good vision. Long-term follow-up studies suggest that recurrences may develop in up to 50% of patients.[2] 
Last updated: 12/30/2009

References
Other Names for this Disease
  • Acute multifocal placoid pigment epitheliopathy
  • Acute placoid pigment epitheliopathy
  • Acute posterior multifocal placoid pigment epitheliopathy
  • AMPPE
  • APMPPE
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.