Charcot-Marie-Tooth disease type 1A
Other Names for this Disease
- Charcot Marie Tooth disease type 1A
- Charcot-Marie-Tooth disease, demyelinating, type 1A
- CMT 1A
- Hereditary motor and sensory neuropathy 1A
- HMSN 1A
Your QuestionMy daughter's father was diagnosed with CMT1A in childhood. My daughter is very active and we decided to not have her tested, unless she shows symptoms. I have noticed that her hands sometimes shake. Should this be a concern? Also she walks on her tip toes. She has since she started walking. However I did too as a child and I don't have the disease. Her father has stated that he has never been physically able to walk on his toes even as a child. I read so many things on the internet and it's so confusing. Her feet do not look abnormal. Anyway I was just wondering about the toe walking and the hands shaking sometimes.
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Questions on this page
Toe walking is not typically an early sign of CMT1A, rather more often it is a "slap foot gait" due to weakness in the lower legs (foot drop). Clumbsiness or frequent tripping are other early signs. As CMT1A progresses a person may develop tight heel cords. Children with tight heel cords often walk on their toes, however toe walking is a common habit among unaffected children as well.
The following online resources can also help you find a professional in your community:
- The National Society of Genetic Counselors provides a searchable directory of US and international genetic counseling services.
- The American College of Medical Genetics has a searchable database of US genetics clinics.
- The Muscular Dystrophy Association offers clinical services throughout the US that provide care to people with CMT.
- The American Academy of Neurology has a Find a Neurologist tool.
- Thomas D Bird. Charcot-Marie-Tooth Neuropathy Type 1. GeneReviews. August 18, 2011; http://www.ncbi.nlm.nih.gov/books/NBK1205/. Accessed 9/7/2012.
- Tremor Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). 2011; http://www.ninds.nih.gov/disorders/tremor/detail_tremor.htm. Accessed 5/11/2011.
- Helibroner PL Castaneda GY. In: Aquino L. Pediatric Neurology: Essentials for General Practice. Philadelphia PA: Lippincott Williams & Wilkins; 2007;