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Juvenile amyotrophic lateral sclerosis

Other Names for this Disease
  • Amyotrophic lateral sclerosis, juvenile
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Juvenile amyotrophic lateral sclerosis (ALS) is a type of motor neuron disease which leads to problems with muscle control and movement.[1][2] Signs and symptoms of juvenile ALS tend to present by age 25 years or younger.  Unlike other types of ALS, juvenile ALS is not rapidly progressive.[3][4] People with juvenile ALS can have a normal life expectancy. Juvenile ALS is often genetic and may be inherited in an autosomal dominant or autosomal recessive fashion.[3][4]

Last updated: 7/8/2013


  1. Amyotrophic Lateral Sclerosis. Genetics Home Reference Web site. August 2007; Accessed 2/7/2008.
  2. Donkervoort S, Siddique T. Amyotrophic Lateral Sclerosis. GeneReviews . 2009; Accessed 4/12/2011.
  3. Orban P, Devon RS, Hayden MR, Leavitt BR. Juvenile Amyotrophic Lateral Sclerosis. Handbook of Clinical Neurology. . 2007;82(3):301-312; Accessed 7/8/2013.
  4. Rabin BA, Griffin JW, Crain BJ, Scavina M, Chance PF, Cornblath DR. Brain . Autosomal dominant juvenile amyotrophic lateral sclerosis. Brain. 1999;122(8):1539-1550; Accessed 7/5/2013.
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  • Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Juvenile amyotrophic lateral sclerosis. Click on the link to view a sample search on this topic.