Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Linear and whorled nevoid hypermelanosis

Other Names for this Disease
  • Linear and whorled hypermelanosis
  • LWNH
  • Nevoid hypermelanosis, linear and whorled
  • Reticulate hyperpigmentation of Iijima
  • Zebra-like hyperpigmentation
More Names
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What are the signs and symptoms of linear and whorled nevoid hypermelanosis?

Signs and symptoms of linear and whorled nevoid hypermelanosis include swirling streaks of hyperpigmented (darkened) skin.  The hyperpigmentation may or may not be apparent at birth, but tends to present by infancy or early childhood. Unlike other rare hyperpigmented skin conditions, the hyperpigmentation occurs without inflammation, blisters, or warty lesions. The hyperpigmentation follows the lines of Blashko and may involve part or much of the body (eyes, palms of the hands, soles of the feet, and mucous membranes are usually not affected). The skin symptoms may progress for one to two years before stabilizing. Children with linear and whorled nevoid hypermelanosis often have otherwise normal physical and neurologic development, however individual cases occurring along with neurologic, heart, growth, and skeletal abnormalities have been described.[1]
Last updated: 3/18/2013

  1. Mehta V, Vasanth V, Balachandran C, Mathew M. Linear and whorled nevoid hypermelanosis. Int J Dermatol. 2011 Apr;50(4):491-2; Accessed 3/18/2013.