MTHFR gene mutation
* Not a rare disease
Other Names for this Disease
- Methylenetetrahydrofolate reductase mutation
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Your QuestionI just found out I also have a MTHFR homozygous A1298C mutation. (the C677T mutation was NOT detected.) What does the combination of these two mutations mean for treatment and further testing recommendations?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Two copies of A1298C are not typically associated with increased homocysteine levels. A mutation in the A1298C gene typically only causes health problems if a person's other gene copy has a mutation in the C677T gene. We recommend you discuss with your doctor if further testing is recommended.
Last updated: 1/22/2014
- Lab Tests Online. MTHFR. September 6, 2011; http://labtestsonline.org/understanding/analytes/mthfr/tab/test. Accessed 1/22/2014.