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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Adult-onset vitelliform macular dystrophy


Other Names for this Disease

  • Adult-onset foveomacular vitelliform dystrophy
  • AVMD
  • Foveomacular dystrophy, adult-onset, with choroidal neovascularization
  • Foveomacular dystrophy, adult-onset; AOFMD
  • Macular dystrophy, vitelliform, adult-onset
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Symptoms

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What are the signs and symptoms of adult-onset vitelliform macular dystrophy?

Signs and symptoms of adult-onset vitelliform macular dystrophy typically begin during mid-adulthood, in the fourth or fifth decade of life.[1][2] At the time of diagnosis, individuals may have minimal visual symptoms (such as mild blurring) or mild metamorphopsia (distorted vision).[2] Cells underlying the macula become more damaged over time, which can cause slowly progressive vision loss.[1] The condition is usually bilateral (affecting both eyes).[2] It usually does not affect peripheral vision or the ability to see at night.[1]

Studies have revealed much variability in the signs, symptoms and progression of this condition. It has been reported that while one individual may not have significant changes in visual acuity over several years, another may experience ongoing visual loss. It has been suggested that in the majority of affected individuals, progression of functional loss is limited.[3] In general, the long-term outlook (prognosis) is usually good, but loss of central visual function is possible.[3]
Last updated: 10/3/2013

References
  1. Vitelliform macular dystrophy. Genetics Home Reference. October 2008; http://ghr.nlm.nih.gov/condition/vitelliform-macular-dystrophy. Accessed 10/3/2013.
  2. Brecher R, Bird AC. Adult vitelliform macular dystrophy. Eye (Lond.). 1990; 4(Pt 1):210-215.
  3. Renner AB. et al. Morphology and functional characteristics in adult vitelliform macular dystrophy. Retina. December 2004; 24(6):929-939.


Other Names for this Disease
  • Adult-onset foveomacular vitelliform dystrophy
  • AVMD
  • Foveomacular dystrophy, adult-onset, with choroidal neovascularization
  • Foveomacular dystrophy, adult-onset; AOFMD
  • Macular dystrophy, vitelliform, adult-onset
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.