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Genetic and Rare Diseases Information Center (GARD)

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Nevus of Ito

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Nevus of Ito is a colored birth mark that is usually slate-brown or blue/gray. It is an unusual birthmark in which the melanocytes (pigment cells) are found deeper than normal in the skin. This type of birthmark is usually located on the shoulder and upper arm area on one side of the body. It can sometimes be associated with sensory changes in the involved skin area. Very rarely does nevus of Ito become cancerous. The exact cause is unknown. They are most commonly found in Asian populations and appear more frequently in females. They are very uncommon in Caucasians.[1][2]
Last updated: 9/28/2011


  1. Naevi of Ota and Ito. DermNet NZ. August 2011; Accessed 9/28/2011.
  2. Nevi of Ota and Ito . eMedicine. July 2008; Accessed 9/28/2011.
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Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Nevus of Ito. Click on the link to view a sample search on this topic.