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Genetic and Rare Diseases Information Center (GARD)

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Logopenic progressive aphasia

Other Names for this Disease
  • Logopenic primary progressive aphasia
  • Logopenic variant PPA
  • LPA
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Logopenic progressive aphasia (LPA) is a type of dementia characterized by language disturbance, including difficulty making or understanding speech (aphasia). It is a type of primary progressive aphasia (PPA). Affected individuals have slow, hesitant speech due to difficulty retrieving the correct words, names, or numbers. Speech is typically well articulated and grammatically correct with good single-word comprehension. But over time, affected individuals may have trouble understanding long or complex verbal information, due to problems holding onto lengthy information that they hear. Language difficulties associated with LPA are due to shrinking, or atrophy, in the left posterior temporal cortex and inferior parietal lobule. Click here to view an image of the lobes of the brain.[1][2]
Last updated: 1/18/2013


  1. Ratnavalli E.. Progress in the last decade in our understanding of primary progressive aphasia. Ann Indian Acad Neurol. 2010; 13:S109-S115. Accessed 2/20/2013.
  2. Primary Progressive Aphasia. UCSF Memory and Aging Center. February 2011; Accessed 9/14/2011.
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In Depth Information

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  • PubMed is a searchable database of medical literature and lists journal articles that discuss Logopenic progressive aphasia. Click on the link to view a sample search on this topic.

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