Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Bilateral frontoparietal polymicrogyria


Other Names for this Disease

  • BFPP
  • Cerebellar ataxia with neuronal migration defect
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Bilateral frontoparietal polymicrogyria (BFPP) is an abnormality of the developing brain in which the brain develops too many folds (which are also unusually small). BFPP specifically affects the frontal and parietal lobes and occurs in both sides of the brain (bilateral). Signs and symptoms of BFPP typically include moderate to severe intellectual disability, motor developmental delay, seizures, cerebellar ataxia, strabismus, dysconjugate gaze (eyes that are not aligned) and other findings. Some cases of BFPP are caused by mutations in the GPR56 gene, and it is inherited in an autosomal recessive manner.[1]
Last updated: 8/24/2011

References

  1. Cassandra L. Kniffin. POLYMICROGYRIA, BILATERAL FRONTOPARIETAL. OMIM. March 27, 2006; http://omim.org/entry/606854. Accessed 8/24/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Bilateral frontoparietal polymicrogyria have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Bilateral frontoparietal polymicrogyria. This website is maintained by the National Library of Medicine.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Bilateral frontoparietal polymicrogyria. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • BFPP
  • Cerebellar ataxia with neuronal migration defect
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.