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Genetic and Rare Diseases Information Center (GARD)

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Hemiplegic migraine

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How might hemiplegic migraine be treated?

Treatment of hemiplegic migraine varies depending on severity and which symptoms are most problematic for the patient. In general, treatments aim to manage symptoms. Drugs that are effective in the prevention of common migraines may be used in hemiplegic migraine.[1] Prophylactic management is applied to patients with frequent, long lasting, or severe attacks. Examples of migraine drugs that have been tried with variable success in people with hemiplegic migraine, include oral verapamil, acetazolamide, lamotrigine.[1]

There are a few articles describing the use of nasal administration of ketamine, intravenous verapamil, and triptans for treatment of aura in people with hemiplegic migraine. Use of triptans in hemiplegic migraine is controversial and may be contraindicated in people with severe attacks.[1]

For further information on these and other treatments, we recommend that you speak with your healthcare provider.
Last updated: 8/26/2013

  1. Jen JC. Familial Hemiplegic Migraine. GeneReviews. September 2009; Accessed 8/26/2013.

Clinical Trials & Research for this Disease

  • lists trials that are studying or have studied Hemiplegic migraine. Click on the link to go to to read descriptions of these studies.