Other Names for this Disease
- Arterial calcification due to CD73 deficiency
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mutations in the NT5E gene. It is inherited in an autosomal recessive manner.ACDC, or aterial calcification due to CD73 deficiency, is a rare, adult-onset vascular disorder. Individuals with ACDC have calcium buildup in their arteries below the waist and in the joints of their hands and feet but not in the arteries of their heart. Affected individuals can experience progressive pain and cramping in the calves, thighs, buttocks and feet due to poor circulation. ACDC is caused by
Last updated: 2/25/2011
- St Hilaire C, Ziegler SG, Markello TC, Brusco A, Groden C, et.al. NT5E mutations and arterial calcifications. N Engl J Med http://www.ncbi.nlm.nih.gov/pubmed/21288095. February 3, 2011;
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- PubMed is a searchable database of medical literature and lists journal articles that discuss ACDC. Click on the link to view a sample search on this topic.
- NIH researchers identify genetic cause of new vascular disease.
Rare disease is first discovered in Undiagnosed Diseases Program