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Astroblastoma
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Overview
Astroblastoma is a rare glial tumor usually located in the cerebral hemisphere of the brain.[1] It can occur in individuals of any age, but occurs predominantly in children and young adults.[2] Signs and symptoms depend on the location and size of the tumor but most commonly include headaches and seizures.[1] Because these tumors are rare, there is little known regarding their behavior and how they should be managed.[3] Gross total resection (complete removal) of the tumor is recommended and is associated with a good prognosis for low-grade tumors. Adjuvant therapy, including radiation and/or chemotherapy, is recommended for high-grade and recurrent cases (although its effectiveness is controversial).[1][4]
References
- Agarwal V, Mally R, Palande DA, Velho V. Cerebral astroblastoma: A case report and review of literature. Asian J Neurosurg. April 2012. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410171/. Accessed September 4, 2012.
- John D. Port, Daniel J. Brat, Peter C. Burger and Martin G. Pomper. Astroblastoma: Radiologic-Pathologic Correlation and Distinction from Ependymoma. AJNR. February 2002.
- Sughrue ME et al. Clinical features and post-surgical outcome of patients with astroblastoma. J Clin Neurosci. June 2011.
- Andrew D Norden, Milan G Chheda, Patrick Y Wen. Uncommon Brain Tumors. UpToDate. Waltham, MA: UpToDate; July 2012.
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General Information
- PubMed is a searchable database of medical literature and lists journal articles that discuss Astroblastoma. Click on the link to view a sample search on this topic.
Selected Full-Text Journal Articles
- Agarwal V, Mally R, Palande DA, Velho V. Cerebral astroblastoma: A case report and review of literature. Asian J Neurosurg. 2012 Apr;7(2):98-100.
- Kemerdere R, Dashti R, Ulu MO, Biçeroglu H, Demiröz AS, Albayram S, Erdinçler P. Supratentorial high grade astroblastoma: report of two cases and review of the literature. Turk Neurosurg. 2009 Apr;19(2):149-52. Review.
- Port JD, Brat DJ, Burger PC, Pomper MG. Astroblastoma: radiologic-pathologic correlation and distinction from ependymoma. AJNR Am J Neuroradiol. 2002 Feb;23(2):243-7.