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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Astroblastoma


Other Names for this Disease

  • Cerebral astroblastoma
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Your Question

Is astroblastoma a brain cancer?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is astroblastoma?

Astroblastoma is a rare glial tumor usually located in the cerebral hemisphere of the brain.[1] It can occur in individuals of any age, but occurs predominantly in children and young adults.[2] Signs and symptoms depend on the location and size of the tumor but most commonly include headaches and seizures.[1] Because these tumors are rare, there is little known regarding their behavior and how they should be managed.[3] Gross total resection (complete removal) of the tumor is recommended and is associated with a good prognosis for low-grade tumors. Adjuvant therapy, including radiation and/or chemotherapy, is recommended for high-grade and recurrent cases (although its effectiveness is controversial).[1][4]
Last updated: 9/4/2012

Is astroblastoma a brain cancer?

Whether a particular astroblastoma is technically non-cancerous or cancerous (malignant) depends on the histological findings (examination of the affected tissue under a microscopic) in each tumor. Malignant astroblastomas are generally characterized by higher cellularity (the number of its constituent cells) and proliferation; necrosis (death of cells or tissues); and vascular proliferation (growth of blood vessels within the tumor).[2]
Last updated: 9/4/2012

References
  • Agarwal V, Mally R, Palande DA, Velho V. Cerebral astroblastoma: A case report and review of literature. Asian J Neurosurg. April 2012; 7(2):98-100. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410171/. Accessed 9/4/2012.
  • John D. Port, Daniel J. Brat, Peter C. Burger and Martin G. Pomper. Astroblastoma: Radiologic-Pathologic Correlation and Distinction from Ependymoma. AJNR. February 2002; 23:243-247.
  • Sughrue ME et al. Clinical features and post-surgical outcome of patients with astroblastoma. J Clin Neurosci. June 2011; 18(6):750-754.
  • Andrew D Norden, Milan G Chheda, Patrick Y Wen. Uncommon Brain Tumors. UpToDate. Waltham, MA: UpToDate; July 2012;
Other Names for this Disease
  • Cerebral astroblastoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.