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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Myxopapillary ependymoma


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Treatment


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How might myxopapillary ependymoma be treated?

Standard treatment of myxopapillary ependymoma is aggressive surgery. It can generally can be cured by gross total surgical resection, and there is usually a favorable prognosis. However, surgery is typically less curative in tumors that are large, multifocal or extend outside the thecal sac. Late recurrences may occur, particularly in pediatric individuals.[1] Treatment strategies may also include radiation, but the use of chemotherapy remains more controversial; chemotherapy has been widely used in pediatric individuals due to more aggressive disease in these individuals.[2] The role of adjuvant chemotherapy or radiotherapy is unclear for the subset of individuals with recurrence or in individuals in whom gross total resection cannot be achieved.[1]
Last updated: 6/8/2011

References
  1. Valerie N Barton et al. Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma. Brain Pathology. May 2010; 20(3):560-570. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871180/?tool=pubmed. Accessed 4/7/2011.
  2. Shonka NA. Targets for therapy in ependymoma. Targeted Oncology. March 29, 2011; Epub:http://www.ncbi.nlm.nih.gov/pubmed/21445635. Accessed 4/7/2011.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Myxopapillary ependymoma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.