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Other Names for this Disease
- Acquired haemophilia
- Hemophilia, acquired
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Acquired hemophilia is a rare form of hemophilia in which the body makes specialized proteins called autoantibodies that attack and disable coagulation factors (proteins in the blood that assist with the clotting process). The most common coagulation factor attacked is coagulation factor VIII, though other coagulation factors, including factor V and factor IX have been associated with the condition. The production of autoantibodies is sometimes associated with pregnancy, immune system disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome), viral infections cancer, or allergic reactions to certain drugs. In about half of cases, the cause of acquired hemophilia is unknown. Treatment may vary from person to person.
- Hemophilia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition=hemophilia. Accessed June 16, 2011.
- Zeitler H, Ulrich-Merzenich G, Hess L, Konsek E, Unkrig C, Walger P, et al. Blood. 2005. http://bloodjournal.hematologylibrary.org/cgi/reprint/105/6/2287. Accessed October 14, 2008.
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- Genetics Home Reference (GHR) contains information on Acquired hemophilia. Click on the link to go to GHR and review the information.
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- !LINK! is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Acquired hemophilia. Click on the link to view a sample search on this topic.