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Genetic and Rare Diseases Information Center (GARD)

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Lymphocytic hypophysitis

Other Names for this Disease
  • Autoimmune hypophysitis
  • LH
  • LYH
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What causes lymphocytic hypophysitis?

The exact cause of lymphocytic hypophysitis (LH) is still under debate and remains unclear. It has been suggested that LH has an autoimmune etiology. This has generally been supported by the frequent postpartum occurrence and the lymphocytic infiltration, as well as several histopathological, laboratory and clinical findings.[1][2]
Last updated: 10/1/2012

  1. Antonio Bellastella, Antonio Bizzarro, Concetta Coronella, Giuseppe Bellastella, Antonio Agostino Sinisi and Annamaria De Bellis. Lymphocytic hypophysitis: a rare or underestimated disease?. European Journal of Endocrinology. 2003; 149:363-376.
  2. Peter J Snyder, MD. Causes of Hypopituitarism. UpToDate. Waltham, MA: UpToDate; 2012;