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Diffuse gastric cancer
Other Names for this Disease
- Signet cell adenocarcinoma
- Signet ring cell carcinoma
- Signet ring cell gastric carcinoma
- Signet ring gastric carcinoma
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Diffuse gastric cancer can be inherited or can happen sporadically in a family. Sporadic means that the cancer occurred randomly for the first time in a individual and was not inherited from a parent. Hereditary diffuse gastric cancer (HDGC) is caused by mutations in the CDH1 gene. Individuals with a CDH1 mutation typically develop cancer before age 40.
Last updated: 12/16/2011
- Kaurah P, Huntsman DG. Hereditary diffuse gastric cancer. GeneReviews. June 2011; http://www.ncbi.nlm.nih.gov/books/NBK1139/. Accessed 9/30/2011.