Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Brugada syndrome


Other Names for this Disease
  • Right bundle branch block, ST segment elevation, and sudden death syndrome
  • Sudden unexpected nocturnal death syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview


Brugada syndrome causes a disruption of the heart's normal rhythm. Signs and symptoms usually develop in adulthood and include ventricular arrhythmia that can cause fainting, seizures, difficulty breathing, or sudden death. These complications typically occur when an affected person is resting or asleep. The underlying cause of Brugada syndrome can not always be identified. In some cases it is due to mutations in the SCN5A gene. Other cases are not genetic (are not due to a gene mutation), but acquired due to adverse reactions to drugs or associated with very low or high levels of potassium, or high levels of calcium.[1]
Last updated: 5/26/2011

References

  1. Brugada syndrome. Genetics Home Reference. 2006; http://ghr.nlm.nih.gov/condition=brugadasyndrome. Accessed 5/26/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Brugada syndrome have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Brugada syndrome. Click on the link to view a sample search on this topic.

Videos/Presentations