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Genetic and Rare Diseases Information Center (GARD)

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Periventricular leukomalacia


Other Names for this Disease
  • PVL
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Overview


Periventricular leukomalacia (PVL) is characterized by the death of the white matter of the brain due to softening of the brain tissue. It can affect fetuses or newborns, and premature babies are at the greatest risk of the disorder. PVL is caused by a lack of oxygen or blood flow to the area around the ventricles of the brain, which results in the death of brain tissue. Although babies with PVL generally have no apparent signs or symptoms of the disorder, they are at risk for motor disorders, delayed mental development, coordination problems, and vision and hearing impairments.[1]
Last updated: 4/29/2008

References

  1. NINDS Periventricular Leukomalacia Information Page . National Institute of Neurological Disorders and Stroke (NINDS). February 7, 2008 ; http://www.ninds.nih.gov/disorders/periventricular_leukomalacia/periventricular_leukomalacia.htm. Accessed 4/29/2008.
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  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.

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