* Not a rare disease
Your QuestionI believe that I may have geographic tongue. Is there treatment for the condition? At what age do symptoms of the condition typically start? I have a family history of psoriasis. Is geographic tongue related to psoriasis? Are the two conditions genetic? Is genetic counseling appropriate for geographic tongue and psoriasis?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- What is geographic tongue?
- What symptoms are seen in geographic tongue?
- At what age do symptoms of geographic tongue typically occur?
- What treatment is available for geographic tongue?
- What causes geographic tongue? Is it genetic?
- Is geographic tongue associated with psoriasis?
- Is psoriasis genetic?
- How can I find out whether recent articles on the association of geographic tongue and psoriasis have been published?
- Should I obtain genetic counseling for geographic tongue and psoriasis?
Specific types of interleukins have also been associated with the lesions seen in psoriasis. Interleukin 12 (IL-12) and interleukin 23 (IL-23) are proteins produced by the body to aid in the fighting off infections. Both IL-12 and IL-23 have been associated with the development of the lesions seen in psoriasis.
It is believed that there are probably other genes that influence the development of psoriasis; therefore, further studies are needed to learn more about which other genes might play a role increasing one's chances of developing the condition.
The National Library of Medicine (NLM) Web site has a page for locating libraries in your area that can provide direct access to these journals (print or online). The Web page also describes how you can get these articles through interlibrary loan and Loansome Doc (an NLM document-ordering service). You can access this page at the following link http://nnlm.gov/members/. You can also contact the NLM toll-free at 888-346-3656 to locate libraries in your area.
Although it is thought that genetic factors influence the development of geographic tongue and psoriasis, much is still unknown about the genetics of the condition. f you are interested in finding out what type of information egarding the genetics of geographic tongue and psoriasis might be overed during a genetics session, we recommend that you contact a genetics clinic near you. To find a genetics clinic near you, we recommend contacting your primary doctor for a referral.
The following online resources can also help you find a genetics professional in your community:
- The National Society of Genetic Counselors provides a searchable directory of US and international genetic counseling services.
- The American College of Medical Genetics has a searchable database of US genetics clinics.
- The University of Kansas Medical Center provides a list of US and international genetic centers, clinics, and departments.
- The American Society of Human Genetics maintains a database of its members, which includes individuals who live outside of the United States. Visit the link to obtain a list of the geneticists in your country, some of whom may be researchers that do not provide medical care.
- Cummings: Otolaryngology: Head and Neck Surgery, 3rd ed. Mosby-Year Book, Inc; 1998;
- Rakel: Conn's Current Therapy 2007, 59th ed.. Saunders; 2007;
- Gonsalves WC, Chi AC, Neville BW. Common Oral Lesions: Part I. Superficial Mucosal Lesions. American Family Physician. February 2007;
- Geographic Tongue. MayoClinic.com. October 20, 2006; http://www.mayoclinic.com/health/geographic-tongue/DS00819/DSECTION=3. Accessed 2/13/2008.
- Guimarães AL, Correia-Silva Jde F, Diniz MG, Xavier GM, Horta MC, Gomez RS. Investigation of funcational gene polymorphisms: IL-1B, IL-6, and TNFA in benign migratory glossitis in Brazilian individuals. J Oral Pathol Med. 2007 Oct;
- Daneshpazhooh M, Moslehi H, Akhyani M, Etesami M. Tongue lesions in psoriasis: a controlled study. BMC Dermatol. 2004 November 4; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC538751/?tool=pubmed. Accessed 2/13/2008.
- Gonzaga HF, Torres EA, Alchorne MM, Gerbase-Delima M. Both psoriasis and benign migratory glossitis are associated with HLA-Cw6. Br J Dermatol. 1996 Sept;
- Zargari O. The prevalence and significance of fissured tongue and geographical tongue in psoriatic patients. Clin Exp Dermatol. 2006 Mar;
- Ferri FF. Ferri: Ferri's Clinical Advisor 2008. Mosby, An Imprint of Elsevier; 2008;
- Emory University School of Medicine. Department of Human Genetics. Division of Medical Genetics. Autoimmune Disorders. 2004; http://www.genetics.emory.edu/pdf/Emory_Human_Genetics_Autoimmune_Disorders.pdf. Accessed 2/14/2008.
- Harris: Kelley's Textbook of Rheumatology, 7th ed.. Saunders, An Imprint of Elsevier; 2005;
- Torti DC, Feldman SR. Interleukin-12, interleukin-23, and psoriasis: Current prospects. J Am Acad Dermatol. December 2007;
- Guilhou JJ, Moles JP. New hypotheses in the genetics of psoriasis and other 'complex' diseases. Dermatology. 2008; http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=18216469%5Buid%5D. Accessed 2/13/2008.