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Selective IgA deficiency
Other Names for this Disease
- Gamma-A-globulin, selective deficiency of
- IgA, selective deficiency of
- Immunoglobulin A deficiency 1
- Immunoglobulin A, selective deficiency of
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autosomal dominant inheritance, others of autosomal recessive inheritance.Selective IgA deficiency refers to the complete or severe deficiency of IgA. This deficiency makes one more prone to infections, allergies, diarrhea, and autoimmune diseases. It is the most common type of primary immunodeficiency and is caused by a lack of mature B-lymphocytes. Why the B-lymphocytes fail to mature and produce IgA is not clear. Familial occurrence has been reported in the medical literature, some cases were suggestive of
Last updated: 8/19/2009
- Selective IgA deficiency. Primary Immunodeficiency Resource Center. http://www.info4pi.org/aboutPI/index.cfm?section=aboutPI&content=syndromes&area=2&CFID=34984195&CFTOKEN=54477486. Accessed 8/19/2009.
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- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Selective IgA deficiency. Click on the link to go to OMIM and review these resources.
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