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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Hemoglobin Zurich


Other Names for this Disease

  • Hb-Zurich
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Symptoms

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What are the signs and symptoms of hemoglobin Zurich?

People with Hemoglobin (Hb) Zurich do not tend to develop symptoms unless their red blood cells are exposed to certain chemicals, infections, or to stress.[1] People with hemoglobin Zurich should avoid sulfanilamide.[2] Some cases of Hb Zurich behave similarly to glucose-6-phosphate dehydrogenase (G6PD) - in that they are especially sensitive to the oxidation of red blood cells.[1] These individuals may benefit from avoiding or limiting exposure to G6PD triggers, such as antimalarial drugs, aspirin, nitrofurantoin, nonsteroidal anti-inflammatory drugs (NSAIDs), Quinidine, Quinine, Sulfonamide, fava beans, and mothballs.

The G6PD Deficiency Association, which is an advocacy group that provides information and supportive resources to individuals and families affected by G6PD deficiency, provides a list of drugs and food ingredients that can trigger hemolytic anemia.
Last updated: 3/20/2014

References
  1. Steinberg MH, Orget BG, Higgs DR, Veatherall DJ. Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management. Oxford: Cambridge University; August 2009; Accessed 3/20/2014.
  2. Steinberg MH. Unstable hemoglobin variants. In: Basow M. UpToDate. Waltham, MA: UpToDate; 2014; Accessed 3/20/2014.
  3. Dugdale DC, Mason JR. Glucose-6-phosphate dehydrogenase deficiency . MedlinePlus. March 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000528.htm. Accessed 10/11/2011.
  4. Benz EJ Jr, Ebert BL. Hemoglobin Variants Associated With Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias. In: Hoffman. Hematology: Basic Principles and Practice, 6th ed. 2012; Accessed 3/20/2014.


Other Names for this Disease
  • Hb-Zurich
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.