Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Hemochromatosis type 2


Other Names for this Disease

  • Hemochromatosis juvenile
  • Iron overload disease juvenile
  • Juvenile hemochromatosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Hemochromatosis type 2 is a disease in which too much iron builds up in the body.  This extra iron is toxic to the body and can damage the organs.[1] Type 2 hemochromatosis is a juvenile-onset disorder. Iron accumulation begins early in life, and symptoms may begin to appear in childhood. Hemochromatosis is inherited in an autosomal recessive manner. It is caused by a mutation in the HAMP or HFE2 gene.[2]

Hemochromatosis may be aquired or inherited. Hereditary hemochromatosis is classified by type depending on the age of onset and other factors such as genetic cause and mode of inheritance.[2] To learn more about other types click on the disease names below:

Hemochromatosis type 1
Hemochromatosis type 3
Hemochromatosis type 4

There is also a neonatal form of hemochromatosis:

Neonatal hemochromatosis

Last updated: 11/21/2010

References

  1. Hemochromatosis. The National Heart, Lung, and Blood Institute (NHLBI). February 2011; http://www.nhlbi.nih.gov/health/dci/Diseases/hemo/hemo_whatis.html. Accessed 8/10/2011.
  2. Hemochromatosis. Genetics Home Reference. 2006; http://ghr.nlm.nih.gov/condition=hemochromatosis . Accessed 8/10/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Hemochromatosis type 2. We will answer your question and update these pages with new resources and information.

Basic Information

  • Genetics Home Reference (GHR) contains information on Hemochromatosis type 2. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hemochromatosis type 2. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Hemochromatosis juvenile
  • Iron overload disease juvenile
  • Juvenile hemochromatosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.